Check Closely (one)crofelemer improves amounts of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch. Crofelemer has the probable to inhibit CYP3A4 at concentrations anticipated inside the gut; not likely to inhibit systemically since minimally absorbed.
Prescribers are strongly suggested to get all fair techniques to make sure that caregivers absolutely have an understanding of their function and obligations vis a vis the administration of diazepam rectal gel to people inside their care
Coadministration of encorafenib with delicate CYP3A4 substrates may possibly cause amplified toxicity or lowered efficacy of such agents.
The above mentioned information and facts is delivered for common informational and educational reasons only. Unique options may possibly vary and formulary data adjustments. Speak to the applicable prepare supplier for probably the most existing information.
fosaprepitant will boost the amount or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Is there any meals or drink I want to stop? You may consume and consume Ordinarily when having dihydrocodeine.
Coadministration of encorafenib with delicate CYP3A4 substrates may perhaps end in greater toxicity or reduced efficacy of those brokers.
It is best to stop consuming alcohol in the initially handful of days of procedure, or if a doctor boosts your dose, until eventually you see how dihydrocodeine affects you.
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VALTOCO website can be a federally controlled compound (CIV) since it is often abused or bring on dependence. Hold VALTOCO in a secure place to prevent misuse and abuse.
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Can I consume Liquor whilst having dihydrocodeine? Drinking Alcoholic beverages whilst you take dihydrocodeine might make you're feeling extra sleepy. It can also improve the threat of serious Unintended effects.
artemether/lumefantrine will minimize the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
diazepam boosts toxicity of oliceridine by Other (see comment). Modify Therapy/Check Intently. Comment: Anticholinergic prescription drugs may possibly improve possibility of urinary retention and/or extreme constipation, which may result in paralytic ileus.